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April 1985

Amyloid Elastosis: A New Cutaneous and Systemic Pattern of Amyloidosis

Author Affiliations

From the Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minn. Dr Venencie is a visiting clinician from the Clinique Dermatologique (Pr A. Puissant), Hôpital St-Louis, Paris.

Arch Dermatol. 1985;121(4):498-502. doi:10.1001/archderm.1985.01660040082016

• A patient with papulonodular cutaneous disease was studied until his death from progressive systemic disease. The elastic fibers in the skin, subcutaneous tissue, and serosae were coated with an amyloid-staining material in a unique pattern, as demonstrated by special stains and electron microscopy. Visceral and cutaneous blood vessels from autopsy tissue also showed amyloidosis, particularly in relation to the elastic fibers. These findings seem to represent a unique syndrome of amyloid disease.

(Arch Dermatol 1985;121:498-502)

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