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May 1985

Penicillamine-Induced Pemphigus Foliaceus-like DermatosisA Case With Unusual Features, Successfully Treated by Plasmapheresis

Arch Dermatol. 1985;121(5):665-668. doi:10.1001/archderm.1985.01660050117029

• A case of a severe, widespread bullous dermatosis clinically resembling pemphigus foliaceus occurred during treatment with penicillamine hydrochloride in a patient with rheumatoid arthritis. Histologically, the disease showed changes compatible with pemphigus vulgaris as well as with a bullous drug eruption. Treatment by plasmapheresis proved to be effective in controlling the disease.

(Arch Dermatol 1985;121:665-668)