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June 1985

Monoclonal Antibody Studies in the Skin Lesions of Patients With Anetoderma

Author Affiliations

From the Department of Dermatology, Mayo Clinic and Mayo Foundation, Rochester, Minn. Dr Venencie is a visiting clinician from the Clinique Dermatologique (Pr A. Puissant), Hôpital Saint Louis, Paris.

Arch Dermatol. 1985;121(6):747-749. doi:10.1001/archderm.1985.01660060061021

• In all five patients studied, monoclonal antibody studies of cryostat sections of skin biopsy specimens of anetoderma lesions revealed inflammatory cells reacting with anti-Leu-1, pan-T-cell antibody, and anti-Leu-3a, the helper/inducer T-cell antibody. Small numbers of suppressor cells were present in only three biopsy specimens. Four specimens showed OKM, antibody-reacting cells (monocytes). The age of the lesion was not correlated with inflammation or the T-cell subsets identified.

(Arch Dermatol 1985;121:747-749)

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