• In all five patients studied, monoclonal antibody studies of cryostat sections of skin biopsy specimens of anetoderma lesions revealed inflammatory cells reacting with anti-Leu-1, pan-T-cell antibody, and anti-Leu-3a, the helper/inducer T-cell antibody. Small numbers of suppressor cells were present in only three biopsy specimens. Four specimens showed OKM, antibody-reacting cells (monocytes). The age of the lesion was not correlated with inflammation or the T-cell subsets identified.
(Arch Dermatol 1985;121:747-749)
Venencie PY, Winkelmann RK. Monoclonal Antibody Studies in the Skin Lesions of Patients With Anetoderma. Arch Dermatol. 1985;121(6):747–749. doi:10.1001/archderm.1985.01660060061021
Customize your JAMA Network experience by selecting one or more topics from the list below.