To the Editor.—
Generalized essential telangiectasia is an uncommon disorder.1-4 It is seen primarily in women,2 is sometimes familial,4 and the average age at onset is 38 years.2 The telangiectasias slowly progress over years or decades2,3 and are not accompanied by associated systemic problems.2 The telangiectasias vary in pattern and distribution and may respond to tetracycline hydrochloride.2,3Unilateral nevoid telangiectasia is a similar but segmental disorder5-8 that is seen more commonly. It usually occurs in women at puberty, during pregnancy, or while taking oral contraceptives5,6 but has also occurred in men with cirrhosis of the liver,6 a finding that is reminiscent of the onset of vascular spiders.7 It was therefore hypothesized that estrogenic stimulation was involved in the pathogenesis of the disorder.6,8 This theory was given considerable impetus in 1983 when Uhlin and McCarty9 found a severalfold
Person JR, Longcope C. Estrogen and Progesterone Receptors Are Not Increased in Generalized Essential Telangiectasia. Arch Dermatol. 1985;121(7):836–837. doi:10.1001/archderm.1985.01660070024007
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