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September 1985

Dermatitis Produced by Applications of Monobenzone in Patients With Active Vitiligo

Author Affiliations

From the Department of Dermatology, University of Cincinnati College of Medicine (Dr Nordlund) and the Departments of Dermatology (Drs Kirkwood and Lerner and Ms Forget) and Medicine (Dr Kirkwood), Yale University School of Medicine, New Haven, Conn.

Arch Dermatol. 1985;121(9):1141-1144. doi:10.1001/archderm.1985.01660090055013

• Six patients with spreading vitiligo treated with applications of monobenzone developed a vesicular dermatitis. The eruption was restricted exclusively to the pigmented areas of the skin. Patch tests applied to pigmented and depigmented skin produced an inflammatory response only within the pigmented areas. The explanation for this puzzling phenomenon is not known.

(Arch Dermatol 1985;121:1141-1144)

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