• Hypopigmentation of hair and freckles occurred in a patient receiving chloroquine sulfate therapy. This patient had a severe congenital renal failure that presumably increased plasma and tissue levels of the drug substantially, accounting for the hypopigmentation.
(Arch Dermatol 1985;121:1164-1166)
André Dupré, Jean-Paul Ortonne, Roland Viraben, Frédéric Arfeux. Chloroquine-Induced Hypopigmentation of Hair and FrecklesAssociation With Congenital Renal Failure. Arch Dermatol. 1985;121(9):1164–1166. doi:10.1001/archderm.1985.01660090078018