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October 1985

Macroglossia: An Unusual Presentation of Pemphigus Vulgaris

Author Affiliations

From the Departments of Dermatology, University of Michigan Medical Center, Ann Arbor (Drs Milgraum, Kanzler, and Waldinger) and Southern California Permanente Medical Group, West Los Angeles (Dr Wong). Dr Wong is now with the Medical Clinic of Sacramento (Calif) Inc.

Arch Dermatol. 1985;121(10):1328-1329. doi:10.1001/archderm.1985.01660100108028

• A 19-year-old woman presented with macroglossia of five months' duration and without bullae or erosions. A biopsy revealed a picture consistent with pemphigus vulgaris. The patient subsequently developed typical oral erosions. Her tongue enlargement and oral ulcerations improved dramatically with topical and systemic steroid therapy. Pemphigus vulgaris should be considered in the differential diagnosis of macroglossia.

(Arch Dermatol 1985;121:1328-1329)

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