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November 1985

Subcutaneous Sclerosis With Fasciitis and Eosinophilia After Phytonadione Injections

Author Affiliations

From the Departments of Pathology and Electron Microscopy (Drs Janin-Mercier and Bourges) and Dermatology (Drs Janin-Mercier, Mosser, and Souteyrand), Centre Hospitalier Universitaire Clermont-Ferrand, France.

Arch Dermatol. 1985;121(11):1421-1423. doi:10.1001/archderm.1985.01660110069018

• We treated a case of subcutaneous sclerosis after phytonadione injections (Texier's disease) that was noteworthy for two associated features: (1) sclerosis with inflammatory infiltrate in the fascia, and (2) blood eosinophilia. A peculiar type of cutaneous sclerosis after phytonadione injections was described in 1972. The sclerosis in that case was first confined to the buttocks, progressively extended to both thighs, and slowly resolved. In the 38 reported cases, neither sclerosis of the fascia nor blood eosinophilia was observed.

(Arch Dermatol 1985;121:1421-1423)