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January 1986

Kyrle's Disease and Hepatic Insufficiency

Author Affiliations

Department of Dermatology Room 137 University of North Carolina School of Medicine Chapel Hill, NC 27514

Arch Dermatol. 1986;122(1):18-19. doi:10.1001/archderm.1986.01660130020013

To the Editor.—  Kyrle's disease is a rare disorder characterized by an often widespread eruption of small to large papules with central keratotic plugs. The majority of patients have associated systemic disease, characteristically overt diabetes mellitus and/or renal disease. However, hepatic disease associated with congestive heart failure has been noted frequently as well.1 We report herein a case of Kyrle's disease associated with alcoholic cirrhosis in the absence of diabetes mellitus, renal disease, or congestive heart failure.

Report of a Case.—  A 46-year-old black man was examined for an asymptomatic and widespread eruption that had been present for many years. There was no history of prior vesicles, trauma, or therapy, and the lesions had gradually become more generalized. His medical history was significant for a long history of alcohol abuse with complications of alcoholic hepatitis, jaundice, ascites, coagulopathy, lower gastrointestinal tract bleeding, anemia, and weight loss. There was no

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