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January 1986

Unusual Locations of Localized Myxedema in Graves' Disease: Report of Three Cases

Author Affiliations

From the Divisions of Dermatology (Dr Noppakun) and Endocrinology (Dr Chandraprasert), Department of Medicine, Chulalongkorn Hospital Medical School, Bangkok, Thailand; and the Department of Medicine, Chonburi (Thailand) Hospital (Dr Bancheun). Dr Noppakun is now with the Department of Dermatology, University of Texas Medical Branch, Galveston, but will return to Chulalongkorn Hospital in June 1986.

Arch Dermatol. 1986;122(1):85-88. doi:10.1001/archderm.1986.01660130089033

• Three patients with Graves' disease had very unusual locations of localized myxedema. One patient had localized myxedema on the pretibial and shoulder areas after sodium iodide I 131 therapy. The second patient had localized myxedema on his neck, shoulders, and upper part of the back as well as on the pretibial area. The third patient had localized myxedema on the pinnae, also following sodium iodide I 131 therapy. After surgical removal followed by intralesional triamcinolone acetonide injections, the first patient's lesions recurred. The lesions in the second case did not respond to topical steroid cream. The third patient had a partial response to intralesional steroid injections.

(Arch Dermatol 1986;122:85-88)