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March 1986

Comparative Efficacy of Treatments for Pediculosis Capitis Infestations

Author Affiliations

From the Departments of Dermatology and Cutaneous Surgery (Ms Meinking and Professor Taplin) and Epidemiology and Public Health (Professor Taplin), University of Miami School of Medicine; the Department of Dermatology, Baylor College of Medicine, Houston (Dr Kalter); and the Department of Entomology, University of California, Berkeley, Arbovirus Field Station, Bakersfield (Dr Eberle).

Arch Dermatol. 1986;122(3):267-271. doi:10.1001/archderm.1986.01660150045013

• Ovicidal activity and killing times were evaluated for six pediculicides, using viable eggs and recently fed head lice from infested children. Lice were continuously exposed to the products until death, and elapsed time was recorded. Eggs were immersed for ten minutes, rinsed, and dried. Four synergized pyrethrin products (RID, R&C Shampoo, A-200 Pyrinate Shampoo, A-200 Pyrinate Liquid) killed all lice in ten to 23 minutes, and 23% to 32% of treated eggs hatched; 0.5% malathion lotion (Prioderm Lotion) killed lice within five minutes and was highly ovicidal, with only 5% of eggs hatching. One percent lindane shampoo (Kwell Shampoo) was the slowest-acting pediculicide, requiring approximately three hours to kill all lice; 30% of the eggs hatched after treatment. The in vitro results for RID, Prioderm Lotion, and Kwell Shampoo were validated by clinical trials.

(Arch Dermatol 1986;122:267-271)

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