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March 1986

Pretibial Epidermolysis Bullosa: Successful Therapy With a Skin Graft

Author Affiliations

From the Departments of Dermatology, University of Tokyo (Drs Furue, Ando, Inoue, Tanaki, and Kukita), and Toranomon Hospital, Tokyo (Dr Oohara).

Arch Dermatol. 1986;122(3):310-313. doi:10.1001/archderm.1986.01660150088022

• A patient with pretibial epidermolysis bullosa was successfully treated with a skin graft. Ultrastructural examination revealed a decreased number of and rudimentary anchoring fibrils (AFs) in the pretibial area in contrast to normal AFs in the grafted skin obtained from a nonpredilection site. Our results indicate the importance of AFs in the pathogenesis of pretibial epidermolysis bullosa.

(Arch Dermatol 1986;122:310-313)

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