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April 1986

Ganglioneuroma of the Skin

Arch Dermatol. 1986;122(4):377-378. doi:10.1001/archderm.1986.01660160027009

To the Editor.—  Ganglioneuromas are composed of mature ganglion cells intermixed with fascicles of spindle cells. These lesions most often arise in association with von Recklinghausen's disease, with neuroblastomas or their metastases. They are usually tumors of the central nervous system or visceral nervous tissue and often occur in childhood.Primary involvement of the skin is rare. To our knowledge, there is only one such case reported in the American literature, and it was noted in a child. We believe ours to be the second case in the American literature, and it was noted as an isolated lesion in an adult.

Report of a Case.—  The patient, a 72-year-old woman in good health, had an asymptomatic cutaneous nodule on her right abdominal wall that had been present for several years. A few weeks before she was seen, the nodule became slightly tender and erythematous. Her medical history was essentially unremarkable