To the Editor.—
The association of vitiligo with autoimmune disorders is well known, but congenital disorders are rare. Described is a patient with ichthyosis vulgaris in whom generalized vitiligo developed at the age of 20 years and whose skin coloration resembled that of a leopard, hence the term leopard vitiligo.
Report of a Case.—
A 20-year-old man with a history of ichthyosis in his family presented with gradually increasing numbers of depigmented patches of ten months' duration over his body. White hairs also developed in all of these patches. Two of his sisters also had ichthyosis, but his three brothers and two other sisters were free of the disease.On examination, his skin was dry and ichthyotic with flaky scales, more so over the arms, legs, chest, and back. Fig 1.—Generalized depigmentation of skin in ichthyotic lesions on forearms and hands. Note raised borders that are normally colored; body hairs