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August 1986

Evaluation of Computed Tomography and Radionuclide Scanning in the Staging of Cutaneous T-Cell Lymphoma

Author Affiliations

From the Departments of Medicine (Drs Rosen, Brennan, and Gordon), Radiology (Dr Gore), Pathology (Dr Variakojis), and Dermatology (Drs Rosenbaum, Caro, and Roenigk), Northwestern University Medical Center and Veterans Administration Lakeside Medical Center, Chicago. Dr Rosenbaum is now with the Department of Dermatology, Rush-Presbyterian-St Luke's Medical Center, Chicago.

Arch Dermatol. 1986;122(8):884-886. doi:10.1001/archderm.1986.01660200056014

• Computed tomography (CT) of the abdomen and pelvis was performed on 30 patients with cutaneous T-cell lymphoma (CTCL) as part of their pretreatment staging evaluation. Twenty-two patients also had liver-spleen radionuclide scans. Physical examination revealed limited cutaneous plaque disease in five patients, extensive plaque disease in 11 patients, cutaneous tumors in six patients, and exfoliative erythroderma in eight patients. Generalized palpable adenopathy was detected in 11 patients, localized palpable adenopathy in ten patients, and no adenopathy in nine patients. Peripheral lymph node biopsy specimens showed CTCL in seven patients and dermatopathic lymphadenitis or sinus histiocytosis in 17 patients. Two patients were at disease stage la, five were at stage lb, seven were at stage IIa, two were at stage IIb, seven were at stage III, and seven were at stage IVa. The CT did not reveal intra-abdominal, retroperitoneal, or pelvic adenopathy, or hepatic or splenic abnormalities in any patient. Radionuclide scans demonstrated nonspecific abnormalities in five patients, but did not appear to reflect disease involvement. Computed tomography of the abdomen and liver-spleen radio-nuclide scans should not be routine staging procedures for CTCL.

(Arch Dermatol 1986;122:884-886)

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