To the Editor.—
Alopecia areata (AA) is a common dermatologic disease, the origin of which is still unknown.1 A number of studies support the hypothesis that at least a subset of alopecia areata may be immunologically mediated. It has, in fact, been associated with some autoimmune diseases and a variable prevalence of both organ- and nonorgan-specific autoantibodies has been detected in this condition.2-4 As far as antihuman parietal cell antibody (HPCA) is concerned, prevalences reported vary from 4% to 6%5,6 to 19%.7 To our knowledge, the titers and the correlation of this antibody with the actual occurrence of autoimmune atrophic gastritis (AG) in alopecia have never been accurately evaluated.On the basis of a previous study performed in a series of unselected patients with vitiligo,8 we have now evaluated patients with alopecia areata to verify the actual association of autoimmune AG with this condition. For
Zauli D, Crespi C, Tosti A, et al. Alopecia Areata. Arch Dermatol. 1986;122(9):975–976. doi:10.1001/archderm.1986.01660210023009
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