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September 1986

Benign Cephalic Histiocytosis

Author Affiliations

From the First Clinic of Dermatology and Pediatric Dermatology, University of Milan (Italy).

Arch Dermatol. 1986;122(9):1038-1043. doi:10.1001/archderm.1986.01660210088025

• Benign cephalic histiocytosis is a self-healing non-X, nonlipid cutaneous histiocytosis of children, characterized by a papular eruption on the head. Mucous membranes and viscera are always spared. In the 13 cases reported herein, the children were otherwise in good general health. The disease appeared during the first three years of life, and spontaneous regression was complete by the age of nine years in the four cases healed to date. The histiocytic infiltrate was localized in the upper and middle dermis and contained no lipids at any stage of evolution. All the histiocytes contained coated vesicles, and 5% to 30% also contained commashaped bodies in their cytoplasm.

(Arch Dermatol 1986;122:1038-1043)

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