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October 1986

Prior Pregnancy and Melanoma Survival

Author Affiliations

Universität-Hautklinik 6500 Mainz Federal Republic of Germany

Arch Dermatol. 1986;122(10):1097. doi:10.1001/archderm.1986.01660220011001

To the Editor.—  Do prior pregnancies influence survival of women with malignant melanoma? In the June 1985 issue of the Archives, Lederman and Sober1 refuted this, and questioned the results of Hersey et al,2 who found a greater survival rate in women older than age 50 years who had been pregnant before their melanoma, compared with nulliparous women.Our clinical studies,3 however, argue for the existence of a certain influence. From the cohort of 2606 patients with melanoma who were seen by the German Melanoma Group (Freiburg, West Germany), we studied the survival rate of 1087 clinical stage I women, with or without pregnancies prior to their cutaneous melanoma. We found a statistically significant higher survival rate in patients younger than age 50 years who had been pregnant five or more times before. In this group, 90% of the women had survived after eight years, but this

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