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November 1986

Diffuse Lipomatosis and Tuberous Sclerosis

Author Affiliations

From the Department of Dermatology, University of California, Irvine, and the Dermatology Service, Veterans Administration Medical Center, Long Beach, Calif.

Arch Dermatol. 1986;122(11):1298-1302. doi:10.1001/archderm.1986.01660230090018

• Diffuse lipomatosis, a classic example of an infiltrating fatty tumor, is a rare entity characterized by infiltration of adult-type adipose tissue into skin, subcutaneous tissue, and muscle. It usually involves a large portion of an extremity or the trunk. Some cases are associated with distant lipomas or angiomas, or hypertrophy of subjacent bone. The association of diffuse lipomatosis with tuberous sclerosis is reported.

(Arch Dermatol 1986;122:1298-1302)