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November 1986

Solitary Nodule on the Foot of a 37-Year-Old Man

Author Affiliations

USN Naval Hospital, Naval Medical Command, National Capital Region, Bethesda, Md

Arch Dermatol. 1986;122(11):1327-1328. doi:10.1001/archderm.1986.01660230119025

REPORT OF A CASE  A 37-year-old man presented to the dermatology clinic for evaluation of a solitary nodule that had been present on the dorsum of his right foot for approximately one year. Examination of the lesion revealed an erythematous, soft, somewhat exophytic, nontender nodule that measured 8 × 10 mm (Fig 1). Results of the remainder of the cutaneous examination were normal. The patient's medical history was otherwise unremarkable.The nodule was excised, fixed in formalin, sectioned, and stained with hematoxylin-eosin. Microscopic examination revealed an intact, atrophic epidermis with overlying hyperkeratosis. The infiltrate of tumor cells formed a poorly demarcated, unencapsulated mass within the dermis that closely abutted but did not invade the epidermis (Fig 2). The infiltrate consisted of many spindle-type cells of various sizes that had hyperchromatic vesicular nuclei and a thin rim of cytoplasm. The infiltrate also contained many pleomorphic, polyhedral, bizarre, multinucleated giant cells whose

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