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December 1986

Scleredema in an Infant

Author Affiliations

From the Department of Dermatology, Groote Schuur Hospital, University of Cape Town (South Africa).

Arch Dermatol. 1986;122(12):1417-1419. doi:10.1001/archderm.1986.01660240081022

• A 3-month-old infant with scleredema had associated cytomegalovirus pneumonia with a rapidly fatal course. Because differentiation of scleredema from sclerema neonatorum, subcutaneous fat necrosis, and scleroderma may be difficult, histologic diagnosis is important. Cetylpyridinium chloride was used successfully as a fixative to demonstrate acid mucopolysaccharides histologically.

(Arch Dermatol 1986;122:1417-1419)