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January 1987

Mycosis Fungoides Associated With Dystrophic Xanthomatosis

Arch Dermatol. 1987;123(1):91-94. doi:10.1001/archderm.1987.01660250097028

• A 59-year-old man with no evidence or history of hyperlipidemia had a dystrophic xanthoma, an accumulation of lipid-rich foam cells in an area of damaged or abnormal skin, that was associated with untreated mycosis fungoides (MF). The patient was subsequently treated with whole-body electron beam therapy. This association of MF and dystrophic xanthoma illustrates histiocyte and xanthoma cell interaction in MF, a cutaneous T-cell lymphoma. Xanthomas may be a cutaneous sign of an underlying lymphoproliferative or myeloproliferative disease in normolipemic patients.

(Arch Dermatol 1987;123:91-94)