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January 1987

Pseudocarcinoma of the Skin

Author Affiliations

Greensboro, NC


by B. A. Berenbien, translated from Russian by V. E. Tatarchenko, 263 pp, with illus, $49.50, New York, Plenum Publishing Corp, 1985.

Arch Dermatol. 1987;123(1):127. doi:10.1001/archderm.1987.01660250135035

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Pseudocarcinoma, as defined by the author, includes not only tumorlike epidermal hyperplasias secondary to chronic inflammation or irritation ("facultative pseudocarcinoma"), but certain primary epidermal hyperplasias ("obligatory pseudocarcinoma"). Facultative pseudocarcinoma corresponds closely with the term pseudoepitheliomatous hyperplasia, which is commonly used in the United States, but the addition of the "obligatory" group—specifically, keratoacanthoma, giant condyloma acuminatum of Buschke and Loewenstein, and papillomatosis carcinomatoides of Gottron—makes pseudocarcinoma a broad and complex term.

The pervasive theme of this treatise is the identification and description of clinical, histologic, chemical, and biologic features that may distinguish pseudocarcinoma from "true" squamous cell carcinoma. There is a five-page side-by-side listing of characteristics that may be of diagnostic value. There is a detailed discussion of quantitative DNA estimations and chromosomal characteristics of cultured cells. The author suggests that these special techniques be used as supportive diagnostic measures in difficult cases, although one can question the feasibility in daily

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