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April 1987

Cryotherapy of Psoriasis

Author Affiliations

Department of Dermatology Medical College of Virginia-Virginia Commonwealth University 1820 Monument Ave Richmond, VA 23220

Arch Dermatol. 1987;123(4):427-428. doi:10.1001/archderm.1987.01660280027011

To the Editor.—  Serendipity, although suffering progressive triteness, does exist. The work discussed here evolved from a chance encounter at a funeral, where Steven L. Blender, MD, recounted his successful trial of cryotherapy of psoriasis to one of my patients. That patient persuaded me to freeze one of his plaques. It resolved and has remained clear for two years.Enthusiasm overcame initial reluctance. During the ensuing year, 31 plaques of 1 to 10 cm in diameter were treated on 12 patients, six men and six women, aged 25 to 73 years. Cryotherapy with liquid nitrogen was performed with a spray or cotton applicator for varying lengths of time. The results, with follow-up periods of one to 11 months, reported to the Virginia Dermatological Society Meeting in Hot Springs, Va, in November 1985, were these: 45% of lesions resolved; an additional 10% cleared except for one or two papular remnants; and