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April 1987

Early Detection of Streptococcal Group Antigens in Skin Samples by Latex Particle Agglutination

Author Affiliations

From the Departments of Dermatology (Drs Bernard, Toty, and Bonnetblanc) and Bacteriology (Drs Mounier and Denis), Centre Hospitalier Regional et Universitaire, Limoges, France.

Arch Dermatol. 1987;123(4):468-470. doi:10.1001/archderm.1987.01660280070025

• The streptococcal group antigens (A to G) were researched in skin biopsy specimens by a latex agglutination technique using commercial (Slidex Streptokit bio-Mérieux and Streptex Wellcome) and experimental reagents. Twenty-seven patients with obvious cutaneous infections (12 cases of erysipelas, nine cases of cellulitis, and six cases of necrotizing fasciitis) and 27 age- and sex-matched controls were studied. Our preliminary data demonstrated the possibility of an early diagnosis of streptococcal cutaneous infections involving the deep dermis and/or hypodermis. We used a latex agglutination technique that is quite specific and gives a better sensitivity (0.63) than either conventional bacteriologic cultures on needle aspiration or skin biopsy specimens.

(Arch Dermatol 1987;123:468-470)

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