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May 1987

Multiple Nodules on the Leg

Author Affiliations

University of Granada (Spain) School of Medicine

Arch Dermatol. 1987;123(5):655-656. doi:10.1001/archderm.1987.01660290123030

REPORT OF A CASE  A 70-year-old woman was examined for the first time in April 1981. She presented with a red and infiltrated nodular lesion (3.5 cm in diameter) on her left leg. The lesion was clinically interpreted as an achromic melanoma or a metastatic carcinoma and was surgically removed and diagnosed histologically as undifferentiated carcinoma. The lung was suggested as a possible primary site. Physical examination did not reveal a primary tumor. In February 1982, the patient returned with six additional cutaneous nodules on the same leg, ranging 3 to 5 cm in diameter. These recurrent lesions were treated with a wide excision. The patient was readmitted to the hospital in October 1982, with several painless nodules on her left leg. The nodules measured 2 to 14 cm in diameter and were covered by thin, shiny, or ulcerated skin (Fig 1). Palpable left inguinal lymph nodes were observed.Representative

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