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May 1987

Morpheic Plaque of the Lower Eyelid

Author Affiliations

Sunnybrook Medical Centre, University of Toronto

Arch Dermatol. 1987;123(5):657-658. doi:10.1001/archderm.1987.01660290125031

REPORT OF A CASE  A 77-year-old retired businessman noted an asymptomatic lesion on his right lower eyelid. He was an avid golfer and had been treated for numerous actinic keratoses and a basal cell carcinoma of the right nasolabial fold in the past. His medical history also included treated pulmonary tuberculosis, carcinoma of the prostate treated with radioactive iodine in 1978, and multifocal transitional cell carcinoma of the bladder, which led to a radical cystectomy in 1981.Examination showed a morpheic plaque on the right lower eyelid margin, extending onto the skin of the eyelid (Fig 1). A skin biopsy specimen showed a normal epidermis with nests of epithelial cells filling the dermis and extending into the underlying muscle of the eyelid (Fig 2). Nuclear atypia was present, and occasional mitotic figures were seen. Some of the nests showed cells with foamy vacuolated cytoplasm (Fig 3).What is your diagnosis?

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