• A 5½ girl with a blistering disease involving the skin and the oral, ocular, and anogenital mucosa is described. The initial clinical, histologic, and immunofluorescence findings suggested a diagnosis of cicatricial pemphigoid. However, immunoelectron microscopy demonstrated linear deposits of several immunoreactants within the sub-lamina densa region of the dermoepidermal junction, consistent with the diagnosis of epidermolysis bullosa acquisita. Although epidermolysis bullosa acquisita is considered a disease of adult onset, it should be included in the differential diagnosis of blistering diseases in children.
(Arch Dermatol 1987;123:772-776)
Rubenstein R, Esterly NB, Fine J. Childhood Epidermolysis Bullosa Acquisita: Detection in a 5-Year-Old Girl. Arch Dermatol. 1987;123(6):772–776. doi:10.1001/archderm.1987.01660300094019
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: