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August 1987

Accelerated Healing of Carbon Dioxide Laser Burns in Rats Treated With Composite Polyurethane Dressings

Author Affiliations

From the Division of Medicine, Walter Reed Army Institute of Research (Dr Chan), Microbiology Branch, US Army Institute of Dental Research (Dr Vincent), Walter Reed Army Medical Center, Washington, DC; and the Department of Preventive Medicine and Biometrics, Uniformed Services University of the Health Sciences, Bethesda, Md (Dr Wangemann).

Arch Dermatol. 1987;123(8):1042-1045. doi:10.1001/archderm.1987.01660320084017

• Healing time, infection rate, and residual scar formation were compared in carbon dioxide laser burns in rats treated in four ways: Spandra composite dressing, OpSite composite dressing, Petrolatum Gauze (USP), and no treatment. There were no infections and no differences in scar formation among the treatment groups. The mean healing times were ten days for the polyurethane dressings (Spandra and OpSite), 13 days for Petrolatum Gauze, and 16 days for the untreated group. Spandra was easier to apply and handle than OpSite. These findings suggest that synthetic gas-permeable dressings promote healing after cutaneous carbon dioxide laser surgery more effectively than conventional treatments of ointment-impregnated gauze or leaving the wound exposed to the air.

(Arch Dermatol 1987;123:1042-1045)

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