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October 1987

Seromucinous (Salivary) Ectopia of the Perianal Region

Author Affiliations

Irwin Memorial Blood Bank 270 Masonic Ave San Francisco, CA 94123

Arch Dermatol. 1987;123(10):1277. doi:10.1001/archderm.1987.01660340037014

To the Editor.—  Seromucinous tissue of salivarygland type has been reported previously in rectal submucosa, in retrorectal cyst hamartomas, and in the prostate gland.1-3 A review of the literature failed to reveal reports of similar ectopic tissue in the perianal region. We are, therefore, reporting the occurrence of seromucinous tissue, typical of the salivary gland, in a perianal fibroepithelial polyp.

Report of a Case.—  A perianal "skin tag" was excised and submitted as an outpatient specimen. The 1.4 × 1.4 × 0.8-cm pale, pink-tan, polypoid tissue had a smooth, glistening surface. Microscopic examination revealed relatively large discrete collections comprising closely packed acini. These structures were lined by a predominant population of mucinous cells, characterized by ample mucoid basophilic cytoplasm and basal nuclei (Fig 1). Lesser numbers of serous cells were present, identified by apical eosinophilic granular cytoplasm and demilune formation (Fig 2). The mucoid elements stained vividly with colloidal

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