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December 1987

Staphylococcal Infections and the Pruritus of AIDS-Related Complex

Author Affiliations

Department of Dermatology The University of Texas Health Science Center Medical School 6431 Fannin, MSB 1.204 Houston, TX 77030

Arch Dermatol. 1987;123(12):1599. doi:10.1001/archderm.1987.01660360027005

To the Editor.—  Dermatologic problems occur in 80% of patients who manifest symptoms of human immunodeficiency virus infection: acquired immunodeficiency syndrome (AIDS)-related complex (ARC) and AIDS. Two of these, especially common in our AIDS dermatology clinic, have not received much attention in the literature.1-3Staphylococcal infections are often found in patients with ARC,4 even at T4 counts of 0.5 × 109/L (500/mm3) in our experience. We have now seen, cultured, and treated 25 cases of intertriginous or axillary staphylococcal infection that look exactly like candidiasis. There are confluent red lesions in the axilla or groin with satellite pustulosis. Cultures have been positive for staphylococcus aureus, resistent to erythromycin therapy, and negative for Candida. The eruption is an atypical presentation of bullous impetigo and responds to dicloxicillin therapy administered orally in several days.The second cutaneous manifestation of ARC is generalized pruritus, which is severe and

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