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May 1988

Bowen's Disease and Internal Malignant Diseases: A Study of 581 Patients

Author Affiliations

From the Department of Dermatology, the Finsen Institute (Drs Reymann, Ravnborg, and Thestrup-Pedersen), and the Danish Cancer Registry (Drs Schou, Engholm, and Osterlind), Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen.

Arch Dermatol. 1988;124(5):677-679. doi:10.1001/archderm.1988.01670050021011

• In a retrospective study of 581 patients with a diagnosis of Bowen's disease (BD) treated over a 40-year period, we traced patient records to identify later diagnoses of nonskin cancer. Fifty patients had nonskin cancer, as against an expected number of 40, but this difference was not significant. The lack of association was equally true for BD on sun-exposed and non-sun-exposed skin. Our findings support the view that BD is not a skin marker for internal malignant disease.

(Arch Dermatol 1988;124:677-679)

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