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August 1988

Pathobiology of Malignant Melanoma

Author Affiliations

Los Angeles

Arch Dermatol. 1988;124(8):1294. doi:10.1001/archderm.1988.01670080094032

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Pathobiology of Malignant Melanoma is an excellent, well-written review of the developmental biology, as well as the clinical, laboratory, epidemiologic, and pathologic aspects, of malignant melanoma. This text is relevant for dermatologists, pathologists, oncologists, and others involved in the care of patients with melanomas. The contributors to this text are leading authorities in the various areas of melanoma research. They include David Elder, Wallace Clark, Mark Greene, Richard Sagebiel, Christain Schmoekel, Otto Braun-Falco, Peter Heenan, Michael Kornstein, and Meenhard Herlyn.

This book has 11 chapters. The first chapter discusses the developmental biology of melanoma. It focuses on tumor progression in relation to nevi and dyplastic nevi. The second chapter comprehensively reviews laboratory studies in hereditary melanoma, which include genetic, cytogenetic, and immunologic studies. This is one of the best and most comprehensive chapters in the text. The third chapter, by Elder and Clark, quite lucidly reviews tumor progression, classification, staging,

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