• Two patients are described in whom a progressive systemic sclerosis-like illness developed several years after silicone augmentation mammoplasty. Both had removal of breast implants, followed by marked-to-complete recovery from clinical abnormalities. This entity is increasingly recognized and has become known as human adjuvant disease.
(Arch Dermatol 1988;124:1383-1386)
Brozena SJ, Fenske NA, Cruse CW, et al. Human Adjuvant Disease Following Augmentation Mammoplasty. Arch Dermatol. 1988;124(9):1383–1386. doi:10.1001/archderm.1988.01670090039008
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