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October 1988

Rapidly Growing, Asymptomatic, Subcutaneous Nodules

Author Affiliations

Veterans Administration Medical Center, San Diego, and University of California, San Diego, School of Medicine

Arch Dermatol. 1988;124(10):1559-1560. doi:10.1001/archderm.1988.01670100061016

REPORT OF A CASE  A healthy 70-year-old man presented with a three-month history of two slowly growing, asymptomatic, subcutaneous nodules located on the right upper arm and the volar aspect of the left forearm (Fig 1). On physical examination, the nodules measured 1.5 cm and 1 cm in diameter, respectively, and were quite firm. The skin overlying them was freely movable, but the nodules were not mobile in the subcutaneous tissue. They did not appear to be fixed to underlying muscle or tendon as they did not move with limb movement.Excisional biopsy was performed and histopathologic features are shown in Figs 2 and 3.What is your diagnosis?

DIAGNOSIS:  Nodular (pseudosarcomatous) fasciitis.

HISTOPATHOLOGIC FINDINGS  Histopathologic examination revealed a poorly circumscribed inflammatory nodule located in the subcutaneous fat. It was composed of a spectrum of cells ranging from fibroblasts to large plump cells with