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October 1988

Functional Abnormality of Horny Layer in Patients With Tinea Pedis

Author Affiliations

Section of Dermatology Ojiya Sougou Hospital Ojiya, Niigata 947, Japan

Arch Dermatol. 1988;124(10):1574. doi:10.1001/archderm.1988.01670100072025

To the Editor.—  Although Trichophyton may play the most important role in the host-parasite relationship in dermatophytosis, local and systemic factors should also be considered.1 It is now suspected that the functional abnormalities of the stratum corneum may greatly influence the infection of Trichophyton as one of various local factors of the host, since Trichophyton is parasitic only on the stratum corneum.

Materials and Methods.—  The hydration state of the superficial portion of the stratum corneum was assessed on the soles of patients with tinea pedis (TP) and on those of healthy subjects by employing an instrument (Skin Surface Hydrometer, IBS Inc, Hamamatsu, Japan) that measures conductance, ie, the reciprocal of resistance, to a high-frequency current (3.5 MHz).2 Some functional parameters (water-holding capacity and hygroscopicity) were compared between the group with TP and the group of healthy subjects to determine whether the soles of patients with TP have