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December 1988

The Perineal Eruption of Kawasaki Syndrome

Author Affiliations

From the Division of Pediatric Dermatology, Children's Hospital Medical Center, Cincinnati, and the Department of Dermatology, The University of Cincinnati College of Medicine. Dr Friter is now in practice in Bricktown, NJ. Dr Lucky is now in private practice in Cincinnati.

Arch Dermatol. 1988;124(12):1805-1810. doi:10.1001/archderm.1988.01670120021004

• The occurrence of a distinctive perineal eruption that appears in infants and children early in the course of Kawasaki syndrome has received little attention in the medical literature. Medical records of patients hospitalized during the acute phase of Kawasaki syndrome were reviewed to evaluate the prevalence of an erythematous, desquamating perineal eruption. The frequency of this eruption was compared with the syndrome's other diagnostic criteria. Thirty-nine (67%) of the 58 patients who fulfilled the criteria for the diagnosis of Kawasaki syndrome had documentation of the perineal rash that usually occurred in the first week of onset of symptoms. No statistically significant differences were found in the frequency of coronary artery aneurysms. We believe that an erythematous, desquamating perineal rash is a valuable early clinical finding facilitating a more rapid diagnosis and treatment of Kawasaki syndrome.

(Arch Dermatol 1988;124:1805-1810)

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