To the Editor.—
We read with interest the May 1988 issue of the Archives that featured articles on the nondermatologic complications of epidermolysis bullosa. We would like to go into more detail about intestinal involvement in dystrophic recessive epidermolysis bullosa (DREB).According to Holbrook1 and Gruskay,2 the simple columnar epithelium could be involved by bullous disease. There is only one detailed report, by Sehgal et al,3 about colonic involvement in DREB. This report refers to clinical and radiologic data, without presenting results from endoscopic and histologic examinations. The other radiologic studies show a normal colon. Colonic interposition is the surgical treatment for tight esophageal strictures. The good results of colonic transplants, described in the same issue, provide experimental proof of the absence of colonic involvement.4According to Gruskay,2 malabsorption could occur subsequent to digestive involvement. In our study of six cases of DREB and review
Fortier-Beaulieu M, de Prost Y. Digestive Involvement in Dystrophic Recessive Epidermolysis Bullosa. Arch Dermatol. 1988;124(12):1870. doi:10.1001/archderm.1988.01670120076021
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