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March 1989

Granulomatous Perioral Dermatitis in Children

Author Affiliations

From the Departments of Dermatology (Drs Frieden and Fletcher), Pediatrics (Dr Frieden), and Pathology (Dr Fletcher), University of California, San Francisco, School of Medicine; the Department of Dermatology, Kaiser Permanente Medical Center, Oakland, Calif (Dr Frieden); the Departments of Dermatology and Pediatrics, State University of New York Health Science Center, Brooklyn (Dr Prose); and the Department of Dermatology, George Washington University School of Medicine, Washington, DC (Dr Turner).

Arch Dermatol. 1989;125(3):369-373. doi:10.1001/archderm.1989.01670150059008

• Five children, aged 3 to 11 years, developed a distinctive perioral, perinasal, and periorbital rash, consisting of tiny, closely spaced, flesh-colored "micronodules." Histopathologic examination in all five cases revealed upper dermal and perifollicular granulomas admixed with lymphocytes. There were no associated systemic abnormalities. The lesions resolved after months to years, leaving no scars. We propose that this condition is a form of perioral dermatitis with granulomatous histologic features, which can be distinguished from sarcoidosis and other facial eruptions in childhood both on clinical and histologic grounds.

(Arch Dermatol 1989;125:369-373)