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March 1989

Eruptive Dysplastic Nevi Associated With Human Immunodeficiency Virus Infection

Author Affiliations

From the Departments of Dermatology and Medicine, University of Texas Health Science Center (Drs Duvic, Rapini, and Lowe); Department of Medicine, University of Texas M. D. Anderson Cancer Center (Drs Duvic and Rodriguez); and the Departments of Dermatology and Pediatrics, Baylor College of Medicine and Texas Children's Hospital (Dr Levy), Houston.

Arch Dermatol. 1989;125(3):397-401. doi:10.1001/archderm.1989.01670150087015

• The cutaneous manifestations of the acquired immunodeficiency syndrome include infections and neoplasms resulting from the immunodeficient state. Seven patients presenting with the symptom of new eruptive nevi with dysplastic histologic findings are described. These patients noted multiple new moles, which occurred in crops and in individuals without the dysplastic nevus syndrome (familial melanomas). This symptom occurred as the patients became symptomatic from their human immunodeficiency virus infection, developing acquired immunodeficiency syndrome or its related complex. Further confirmation and study of this phenomenon could lead to a better understanding of the pathogenesis of melanocytic dysplasia and its relationship to the immune system.

(Arch Dermatol 1989;125:397-401)

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