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May 1989

Lichen Planus Pemphigoides With Features of Lichen Planus and Pemphigus Vulgaris

Author Affiliations

Department of Dermatology; Clinical Laboratory Beilinson Medical Center Petah Tiqva 49100, Israel

Arch Dermatol. 1989;125(5):707-708. doi:10.1001/archderm.1989.01670170123025

To the Editor.—  Since the establishment of immunofluorescence techniques, there has ceased to be a controversy concerning the nosologic relation of lichen planus pemphigoides. The coexistence of lichen planus with a primary bullous disorder, once thought to represent a form of bullous lichen planus, was shown in most cases to have the immunologic characteristics of bullous pemphigoid.1We describe a patient suffering from a rare variant of lichen planus pemphigoides, having the histologic features of both lichen planus and pemphigus vulgaris, confirmed by immunofluorescence.

Report of a Case.—  A 76-year-old woman was admitted to our department with a 2-month history of a generalized eruption consisting of hyperpigmented papules, which was followed one month later by the appearance of loose vesicles and bullae. Four years previously, she had received irradiation with roentgen rays with combination chemotherapy for intra-abdominal lymphoma.On examination, the patient was found to be febrile

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