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September 1989

Unusual Cutaneous Cytomegalovirus Involvement in Patients With Acquired Immunodeficiency Syndrome

Author Affiliations

From the Department of Public Health, Parasitology, and Tropical Medicine and INSERM U3B, Hôpital de la Salpêtrière, Paris, France (Drs Bournérias, Patey, Gharakhanian, Duflo, and Gentilini); the Dermatology Service, Hôpital Henri Mondor, Université Paris Val-de-Marne, Créteil, France (Dr Bournérias); the Anatomy-Pathology Service, Hôpital de la Pitié, Paris, France (Dr Boisnic); and the Virology Service, Hôpital Trousseau, Paris, France (Dr Deny).

Arch Dermatol. 1989;125(9):1243-1246. doi:10.1001/archderm.1989.01670210081012

† Two patients with acquired immunodeficiency syndrome presented unusual keratotic cutaneous lesions with a protracted course. Pathologic examination in both patients, cultures, and DNA hybridization techniques of skin biopsy specimens in the second patient were characteristic of cytomegalovirus cutaneous infection. Cytomegalovirus skin lesions are rarely described in acquired immunodeficiency syndrome in contrast with the high frequency of ocular and visceral involvement. Skin biopsy specimens may lead to early diagnosis of cytomegalovirus disseminated disease and to specific treatment.

(Arch Dermatol. 1989;125:1243-1246)