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December 1989

Generalized Eruptive Clear-Cell Syringoma

Author Affiliations

Department of Dermatology Fukui Red Cross Hospital

Ieki Dermatology Clinic Fukui 910, Japan

Department of Dermatology Faculty of Medicine Kyoto University Kyoto 606, Japan

Arch Dermatol. 1989;125(12):1716-1717. doi:10.1001/archderm.1989.01670240118034

To the Editor.—  Clear-cell syringoma, an unusual variant type of syringoma,1 has two noteworthy features: histologic preponderance of clear cells1 and frequent coexistence with diabetes mellitus.2Eruptive generalized clear-cell syringoma is extremely rare. To our knowledge, only one case3 among 32 cases of clear-cell syringoma was so far reported in English-language and Japanese literature.We recently encountered a case of generalized eruptive clear-cell syringoma. Herein, we describe the case and discuss the relationship between diabetes mellitus and clear-cell syringoma.

Report of a Case.—  A 63-year-old man had many asymptomatic, small papules that had been gradually developing on his trunk and extremities over the past 3 years. He had no remarkable history, except for type II diabetes mellitus of 30 years' duration, which was well controlled by oral hypoglycemic drugs.On physical examination, there were multiple, oval, brown, soft papules (2 to 3 mm) on his chest,

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