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April 1990

Trends in Human Hair Growth and Alopecia Research

Arch Dermatol. 1990;126(4):554. doi:10.1001/archderm.1990.01670280140043

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This book is a collection of papers presented at an international conference, The Human Hair Follicle in Biomedical Research Symposium, held in Brussels, Belgium, in 1988. Most of the contributors are from Europe, with one each from the United States, Japan, and the United Kingdom. The contents reflect the increasing collaboration between dermatological investigators and the pharmacological and cosmetic industries in the study of human hair growth.

Part I, Biology and Experimental Models, starts with a good description of the embryogenesis of the hair follicle and hair cycle. It is interesting to learn that the hair cycle pattern in man and guinea pig is mosaic, in rodents wavelike, and in most other mammals synchronous, but in merino sheep, angora rabbits, and poodle dogs it is not evident and molting never occurs. Next, the current knowledge about the eight hard α-keratins and their molecular markers in hair and nail differentiation is

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