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June 1990

Acquired Ichthyosis in a Patient With Systemic Lupus Erythematosus

Author Affiliations

Department of Internal Medicine

Department of Dermatology Hospital Clinico y Provincial Villarroel 170 08036 Barcelona, Spain

Arch Dermatol. 1990;126(6):829. doi:10.1001/archderm.1990.01670300129027

To the Editor.—  Skin lesions occur in up to 85% of patients with systemic lupus erythematosus (SLE). The most common lesions include malar butterfly rash and photosensitivity dermatitis.1,2 Uncommon manifestations include porphyria, lichen planus, and psoriasis.1 We describe a patient who developed an acquired ichthyosis at the same time that symptoms of SLE began, and disappeared when lupus manifestations regressed under treatment.

Report of a Case.—  A 31-year-old woman who was 20 weeks pregnant presented with a 1-month history of fever, polyarthritis, and pericarditic chest pain. She had skin changes that began at the onset of her disease. Family and personal history were unremarkable. Her temperature was 38.3°C, skin and mucous membranes were pale, and mouth ulcers were present. There were dry, hyperpigmented, well-demarcated scaly areas on her trunk, arms, and thighs, as well as a fine diffuse scaling. Her lungs were normal, and there was a pericardial

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