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July 1990

Radiation-Induced Squamous Sialometaplasia

Author Affiliations

From the Departments of Dermatology (Drs Leshin and White), Pathology (Dr White), and Otolaryngology (Drs Leshin and Koufman), Bowman Gray School of Medicine, Wake Forest University, Winston-Salem, NC.

Arch Dermatol. 1990;126(7):931-934. doi:10.1001/archderm.1990.01670310093014

• We describe a patient with recurrent acantholytic squamous cell carcinoma following radiation therapy. Mohs micrographic sections revealed extensive squamous sialometaplasia showing striking histologic similarity to the patient's squamous cell carcinoma. Criteria necessary to differentiate squamous sialometaplasia from neoplasm are presented. This differentiation is important to ensure adequate tumor resection without unnecessary sacrifice of tumor-free tissue.

(Arch Dermatol. 1990;126:931-934)

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