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September 1990

Congenital Multiple Plaquelike Glomus Tumors

Author Affiliations

From the Departments of Dermatology, Ludwig-Maximilians Universität at Munich (Drs Landthaler, Braun-Falco, Eckert, Stolz, and Dorn) and Medizinische Universität at Lübeck (Dr Wolff).

Arch Dermatol. 1990;126(9):1203-1207. doi:10.1001/archderm.1990.01670330083012

• We encountered two patients with congenital multiple plaquelike glomus tumors. These lesions were present at birth and enlarged with body growth, attaining a diameter of up to 13 cm. The diagnosis was confirmed by histologic and electron-microscopic examination, which revealed the typical changes of glomus tumors. Immunocytochemistry findings demonstrated the tumor cells to be vimentin-and α-smooth muscle-actin-positive and desmin-negative. On ultrastructural examination, typical dense bodies and attachment plaques were easily found within the tumor cells. Glomus cells were coated by a thick basal lamina.

(Arch Dermatol. 1990;126:1203-1207)

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