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November 1990

A Pruritic Vesicular Eruption

Author Affiliations

University of North Carolina, Chapel Hill

Arch Dermatol. 1990;126(11):1499-1500. doi:10.1001/archderm.1990.01670350113021

REPORT OF A CASE  A 13-year-old black girl presented with a 2-week history of a generalized pruritic eruption. The eruption began on the anticubital fossae, with spread to her trunk and extremities over the subsequent 3 days. She had no history of fever, sore throat, nausea, or diarrhea. She had taken no medications.On physical examination, she was a well-appearing, scratching adolescent with 2- to 6-mm vesicles over her entire surface, except for her face and scalp (Fig 1). The palms and soles were also involved. Salmoncolored, oval, scaly, 1- to 3-cm patches were also present on her lower abdomen and chest (Figs 2 and 3).Histopathologic examination of a wrist vesicle revealed intraepidermal blister formation with spongiosis, lymphocytic exocytosis, and focal parakeratosis. There was also a superficial perivascular, mononuclear infiltrate (Fig 4). A periodic acid-Schiff stain was negative for fungal elements. Results from a rapid plasma reagin test were

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