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February 1991

Intralesional Bleomycin Sulfate Therapy for Warts: A Novel Bifurcated Needle Puncture Technique

Author Affiliations

From the Division of Dermatology, Department of Medicine, Medical College of Ohio, Toledo.

Arch Dermatol. 1991;127(2):234-236. doi:10.1001/archderm.1991.01680020102014

• A multiple puncture technique using a bifurcated vaccination needle to introduce bleomycin sulfate (1 U/mL sterile saline solution) into warts resulted in elimination of 92% of a random series of 258 warts after a single treatment. Recurrence was not observed during a 6-month follow-up period. Six of the 66 patients required two to seven treatments for wart eradication, and four patients requested alternative therapy after initial failure with a single bleomycin treatment.

(Arch Dermatol. 1991;127:234-236)

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